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The analysis of Chromosome Mapping stained chromosomes is the main activity of the restrain called cytogenetics. deoxyribonucleic acid stains illicit a reproducible banding ensample on chromosomes Quinacrine and Giemsa: DNA dye- chromosome specific pattern Has allowed to for use of regions in a chromosome p and q arms and different regions Quinacrine, a chemic relative of the antimalarial drug quinine, was wizard of the setoff of these more discriminating reagents. Chromosomes that ca-ca been stained with mepacrine repoint a characteristic pattern of bright bands on a darker background. However, because quinacrine is a fluorescent compound, the bands appear all when the chromosomes be loose to ultraviolet (UV) light. Ultraviolet irradiation causes some of the quinacrine molecules that have inserted into the chromosome to emit energy. Excellent nonfluorescent staining techniques have in addition been developed. The close to popular of these uses Giemsa stain, a mixture of dyes named after its inventor, Gustav Giemsa. same(p) quinacrine, Giemsa creates a reproducible pattern of bands on each chromosome. 4 ^^^^^Chromosome painting. Probesmade from human DNA have been applied to aspread of human chromosomes.

to each one probe hasbeen designate with a dye that fluoresces a differentcolor ( ping or bright spirt) to chance on where Fragments are a specific complementary color sequence .. pink is the centromere, green is the sequence specific to three chromosomes DNA sequences complementary to these probesare dictated in the chromosomes. The pink probeta rgets DNA in the centromere of each chromos! ome,whereas the bright green probe targets DNA in only three pairs of chromosomes. Treat mitotic spreads with DNA fragments labelled with flurochromes-Any of a assembly of fluorescent dyes used to stain biological specimens. Chromosome Variation A karyotype shows the duplicated chromosomes of a cell arranged for cytogenetic analysis (46 xx Euploid- one set of chromosomes Polyploid-...If you want to get a climb essay, ordinate it on our website: OrderCustomPaper.com

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